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VOLUME 48 , ISSUE 3 ( July-September, 2014 ) > List of Articles


Pediatric Dental Sedation Practice: Evolution and Current State-of-the-Art

Neeti Mittal

Citation Information : Mittal N. Pediatric Dental Sedation Practice: Evolution and Current State-of-the-Art. J Postgrad Med Edu Res 2014; 48 (3):139-147.

DOI: 10.5005/jp-journals-10028-1119

Published Online: 01-09-2014

Copyright Statement:  Copyright © 2014; The Author(s).


How to cite this article

Mittal N, Gauba K, Goyal A, Kapur A. Pediatric Dental Sedation Practice: Evolution and Current State-of-the-Art. J Postgrad Med Edu Res 2014;48(3):139-147.

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  1. Challenges of managing child behavior in the 21st century dental setting. Pediatr Dent 2004;26(2):111-113.
  2. Managing pediatric dental patients: issues raised by the law and changing views of proper child care. Pediatr Dent 2004;26(2):125-130.
  3. Fear of dentistry: a discussion of its usefulness to certain dental patients. ASDC J Dent Child 1983;50(2):111-113.
  4. Pharmacological management of the pediatric dental patient. Pediatr Dent 2004;26(2):131-136.
  5. The need for sedation in conservative dentistry. An investigation in the inner London area. Br Dent J 1970;128(1):19-22.
  6. A review of the pharmacological approach to the management of dental anxiety in children. Int J Paediatr Dent 2002;12(5):347-354.
  7. Dexmedetomidine versus midazolam in outpatient third molar surgery. J Oral Maxillofac Surg 2006;64(9):1353-1358.
  8. Dexmedtedomidine: a potential agent for use in procedural dental sedation. Ind J Dent 2014;5:21-27.
  9. Comparative study between novel sedative drug (dexmedetomidine) versus midazolampropofol for conscious sedation in pediatric patients undergoing oro-dental procedures. Egypt J Anaesthesia 2010;26(4):299-304.
  10. Procedural sedation and analgesia in children. Lancet 2006;367(9512):766-780.
  11. Efficacy and acceptabilty of oral-transmucosal midazolam as conscious sedation agent in pre-school children. J Indian Soc Pedod Prev Dent 2004;22(3):109-113.
  12. The physiologic and behavioral effects of oral and intranasal midazolam in pediatric dental patients. Pediatr Dent 2010;32(3): 229-238.
  13. Propofol an update of its use in anesthesia and conscious sedation. Drugs 1995;50(3):513-559.
  14. A randomized doubleblinded trial of chloral hydrate with or without hydroxyzine versus placebo for pediatric dental sedation. Braz Dent J 2007; 18(4):334-340.
  15. Sedative effect of oral diazepam and chloral hydrate in the dental treatment of children. J Indian Soc Pedod Prev Dent 2007;25(2):69-75.
  16. A randomized double-blind trial of chloral hydrate/hydroxyzine versus midazolam/acetaminophen in the sedation of pediatric dental outpatients. ASDC J Dent Child 1996;63(2):95-100.
  17. Management of the refractory young child with chloral hydrate: dosage selection. ASDC J Dent Child 1987; 54(2):93-100.
  18. Sedation for pediatric dental patients: a review. Pediatr Clin North Am 1994;41(1):31-35.
  19. Sedation of children for electroencephalograms. Pediatrics 2001; 108(1):163-165.
  20. High-dose chloral hydrate sedation for children undergoing MR imaging: safety and efficacy in relation to age. AJR Am J Roentgenol 1993; 161(3):639-641.
  21. Death after chloral hydrate sedation: report of a case. J Am Dent Assoc 1988;116(3):345-348.
  22. Adverse events and risk factors associated with the sedation of children by nonanesthesiologists. Anesth Analg 1997;85(6):1207-1213.
  23. Adverse sedation events in pediatrics: analysis of medications used for sedation. Pediatrics 2000;106(4):633-644.
  24. Use of chloral hydrate for sedation in children. Pediatrics 1993;92(3): 471-473.
  25. Sedation: a guide to patient management. 5th ed. Missouri: Mosby Elsevier; 2010.p.624.
  26. The effectiveness of midazolam and hydroxyzine as sedative agents for young pediatric dental patients. ASDC J Dent Child 1996; 63(6):421-425.
  27. Pharmacological patient management in pediatric dentistry: An Update. ASDC J Dent Child 1993;60(4-5):270-280.
  28. A comparison of two meperidine/hydroxyzine sedation regimens for the uncooperative pediatric dental patient. Pediatr Dent 2005;27(5):395-400.
  29. A comparative evaluation of oral Midazolam with other sedatives as premedication in pediatric dentistry. J Clin Ped Dent 2002;26(2):161-164.
  30. Methods for behaviour research on dentally anxious children. The example of relative analgesia. Br Dent J 1980;149(6):175-179.
  31. Premedication with flunitrazepam, diazepam and placebo in the apprehensive child. ASDC J Dent Child 1984;51(3):208-210.
  32. A study to compare the effectiveness of temazepam and a chloral hydrate/hydroxyzine combination in sedating paediatric dental patients. Int J Paediatr Dent 1992;2(3):163-169.
  33. Experience with triazolam in preschool children. Anesth Pain Control Dent 1992;1(3):157-159.
  34. The safety and efficacy of using a concentrated intranasal midazolam formulation for paediatric dental sedation. SAAD Dig 2011;27:16-23.
  35. Efficacy and acceptabilty of oral-transmucosal midazolam as a conscious sedation agent in pre-school children. J Indian Soc Pedod Prev Dent 2004;22(3):109-113.
  36. Current theories about the mechanism of benzodiazepine and neuroleptic drugs. Anesthesiology 1981;54(1):66-72.
  37. Post-discharge adverse events following pediatric sedation with high doses of oral medication. J Pediatr 2012;160(5): 807-813.
  38. Comparison of oral midazolam and nitrous oxide sedation for dental extractions in children. Anaesthesia 2006;61(12):1138-1144.
  39. A double blind randomized trial of Ketofol versus Propofol in anxious pediatric patients. J Clin Pediatr Dent 37(4):415-420.
  40. A comparative evaluation of intranasal midazolam, ketamine and their combination for sedation of young uncooperative pediatric dental patients: a triple blind randomized crossover trial. J Clin Pediatr Dent 2011;35(4):415-420.
  41. Advanced paediatric conscious sedation: an alternative to dental general anaesthetic in the UK. SAAD Dig 2011;27:24-29.
  42. Use of IV fentanyl in the outpatient treatment of pediatric facial trauma. J Trauma 1985;25(11):1079-1080.
  43. Pharmacological aspects and potential new clinical applications of ketamine: reevaluation of an old drug. J Clin Pharmacol 2009; 49(8):957-963.
  44. Dental anesthesia and pediatric dentistry. Anesth Prog 1995;42:95-99.
  45. Predictors of emesis and recovery agitation with emergency department ketamine sedation: an individual-patient data metaanalysis of 8,282 children. Ann Emerg Med 2009;54(2):171-180.
  46. Predictors of airway and respiratory adverse events with ketamine sedation in the emergency department: an individualpatient data meta-analysis of 8,282 children. Ann Emerg Med 2009;54(2):158-168.
  47. Emergency department ketamine meta-analysis study group. Laryngospasm during emergency department ketamine sedation a case-control study. Pediatr Emerg Care 2010;26(11):798-802.
  48. Respiratory arrest following intramuscular ketamine injection in a 4-year-old child. Ann Emerg Med 1993; 22(3):613-615.
  49. Relative potency of eltanolone, propofol and thiopental for induction of anesthesia. Anesthesiology 1994;80(1):36-40.
  50. Potency of propofol for loss of consciousness after a single bolus dose. Br J Anesth 1990;64:743-746.
  51. Induction dose-responses studies with propofol and thiopentone. Br J Anesth 1992;68(3):308-310.
  52. A clinical trial of propofol vs midazolam for procedural sedation in a pediatric emergency department. Acad Emerg Med 1999;6(10):989-997.
  53. Propofol sedation: intensivists’ experience with 7304 cases in a children's hospital. Pediatrics 2007;120(6):e1411–e1417.
  54. Propofol sedation with fentanyl or midazolam during oesophagogastroduodenoscopy in children. Eur J Anaesthesiol 2005;22(11):848-852.
  55. Synergistic sedation with oral midazolam as a premedication and intravenous propofol versus intravenous propofol alone in upper gastrointestinal endoscopies in children: a prospective, randomized study. J Pediatr Gastroenterol Nutr 2006;43(2):195-199.
  56. Analgesia and sedation in intensive care unit. Rev Bras Anestesiol 2010;60(6):648-658.
  57. Drugs of choice for sedation and analgesia in the neonatal ICU. Clin Perinatol 2009;36(2):215-226.
  58. Propofol intravenous conscious sedation for anxious children in a specialist paediatric dentistry unit. Int J Paediatr Dent 2004; 14(1):2-8.
  59. Nitrous oxide oxygen sedation in dentistry. Swed Dent J Suppl 1982;14:s9-10.
  60. A comparison of inhalation sedation agents in the management of children receiving dental treatment: a randomized, controlled, cross-over pilot trial. Int J Paediatr Dent 2010;201:65-75.
  61. General anaesthesia, sedation and resuscitation in dentistry. Report of an expert working party. London: Department of Health, 1990.
  62. A conscious decision: A review of the use of general anaesthesia and conscious sedation in primary dental care. Report of a group chaired by the chief medical and chief dental officer. 2000. Available at: and Statistics/Publications. Accessed on 20 February 2013.
  63. UK national clinical guidelines in paediatric dentistry. managing anxious children: the use of conscious sedation in paediatric dentistry. Int J Paediat Dent 2002;12(5):359-372.
  64. Safe sedation of children undergoing diagnostic and therapeutic procedures 2002; revised on 2004. Available at: Accessed on 20 February 2013.
  65. conscious sedation in the provision of dental care. Report of an expert group on sedation for dentistry. 2003. Available at: Accessed on 20 February 2013.
  66. Standards for dental professionals, 2005. Available at: Accessed on 20 February 2013.
  67. Conscious sedation in dentistry, dental clinical guidance, 2006. Available at: Accessed on 20 February 2013.
  68. Guidelines for the elective use of conscious sedation, deep sedation, and general anesthesia in pediatric patients. Pediatrics 1985;76:317-321.
  69. Guidelines for the elective use of conscious sedation, deep sedation, and general anesthesia in pediatric patients. ASDC J Dent Child 1986;53:21-22.
  70. Pediatrics 1992;89:1110-1115.
  71. Anesthesiology 2002;96:1004-1017.
  72. Reference Manual 1999-2000. American Academy of Pediatric Dentistry, 1998:68-73.
  73. Guidelines for monitoring and management of pediatric patients during and after sedation for diagnostic and therapeutic procedures: an update. Pediatrics 2006;118:2587-2602.
  74. Sedation protocols-why so many variations? Pediatrics 1994;94:281-283.
  75. Round and round we go: sedation-what is it, who does it, and have we made things safer for children? Pediatr Anesth 2008;18:3-8.
  76. Conscious sedation in pediatric dentistry. A short review of the current UK guidelines and the technique of inhalational sedation with nitrous oxide. Pediatric Anesthesia 2008; 18(1):13-17.
  77. Sedation of children undergoing dental treatment. Cochrane Database Syst Rev 2012;14:CD003877.
  78. Safety of oral midazolam sedation use in paediatric dentistry: a review. Int J Paediatr Dent 2014;24(1):2-13.
  79. Bispectral Index: Validity and utility in pediatric dental sedation. J Clin Pediatr Dent 2014; 38(4):290-295.
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