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VOLUME 49 , ISSUE 3 ( July-September, 2015 ) > List of Articles


Total Knee Arthroplasty in a Case of Tuberculosis Knee in Healing Stage: Is it Safe?

Sanjay Yadav, Chandra Shekhar Yadav, Nishikant Kumar

Citation Information : Yadav S, Yadav CS, Kumar N. Total Knee Arthroplasty in a Case of Tuberculosis Knee in Healing Stage: Is it Safe?. J Postgrad Med Edu Res 2015; 49 (3):139-142.

DOI: 10.5005/jp-journals-10028-1163

Published Online: 00-09-2015

Copyright Statement:  Copyright © 2015; Jaypee Brothers Medical Publishers (P) Ltd.



Association of tuberculosis and total hip joint replacement (THR) is described with or without antitubercular treatment (ATT) cover but total knee arthroplasty (TKA) in early disease in single-stage is uncommonly reported. We wish to share our clinical experience in such a case.

Case description

A 22-year-old male presented with pain and swelling of left knee for 7 months. It was drained at local health facility with sinus development. Tuberculosis was diagnosed by clinic-radiological evaluation and ATT was started. Sinus healed but disabling pain and knee stiffness with flexion deformity persisted. Radiographs revealed destructive osteoarticular arthritis with periarticular osteopenia. Debridement followed by TKA in single-stage was done with posterior-stabilized implant. Postoperative period was uneventful. Histopathological analysis confirmed chronic granulomatous synovitis with caseation necrosis suggestive of mycobacterial infection. After 1-year, ATT was discontinued and patient was disease-free.

Clinical relevance

Single-stage prosthetic knee joint arthroplasty can be safely performed under adequate ATT coverage in early disease provided response to medical treatment is good. Patient counseling regarding compliance with ATT and postoperative protocol is important in ensuring success.

How to cite this article

Yadav S, Yadav CS, Kumar N, Kumar A. Total Knee Arthroplasty in a Case of Tuberculosis Knee in Healing Stage: Is it Safe? J Postgrad Med Edu Res 2015;49(3): 139-142.

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