The Effect of Erythropoietin on Amylase Levels during Ischemia-Reperfusion Injury in Rats
Constantinos Tsompos, Constantinos Panoulis, Konstantinos Toutouzas, George Zografos, Apostolos Papalois
Citation Information :
Tsompos C, Panoulis C, Toutouzas K, Zografos G, Papalois A. The Effect of Erythropoietin on Amylase Levels during Ischemia-Reperfusion Injury in Rats. J Postgrad Med Edu Res 2016; 50 (1):18-21.
Forty rats of mean weight 247.7 gm were used in the study. Amylase levels were measured at 60 minutes (groups A and C) and at 120 minutes (groups B and D) of reperfusion. Erythropoietin was administered only in groups C and D.
Results
Erythropoietin administration kept non-significantly increased the A levels by 5.04 ± 6.12% (p = 0.3831). Reperfusion time kept non-significantly increased the A levels by 10.08 ± 5.95% (p = 0.0615). However, EPO administration and reperfusion time together produced a non-significant combined effect in keeping increased the A levels by 4.36 ± 3.65% (p = 0.2258)
Conclusion
Erythropoietin administration, reperfusion time and their interaction kept non-significantly short-term increased the amylase levels. The restorating effect of Epo is satisfactory, since it reduced the discrepancy from baseline values at non-significant level.
How to cite this article
Tsompos C, Panoulis C, Toutouzas K, Zografos G, Papalois A. The Effect of Erythropoietin on Amylase Levels during Ischemia-Reperfusion Injury in Rats. J Postgrad Med Edu Res 2016;50(1):18-21.
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