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VOLUME 50 , ISSUE 1 ( January-March, 2016 ) > List of Articles

RESEARCH ARTICLE

The Effect of Erythropoietin on Amylase Levels during Ischemia-Reperfusion Injury in Rats

Constantinos Tsompos, Constantinos Panoulis, Konstantinos Toutouzas, George Zografos, Apostolos Papalois

Citation Information : Tsompos C, Panoulis C, Toutouzas K, Zografos G, Papalois A. The Effect of Erythropoietin on Amylase Levels during Ischemia-Reperfusion Injury in Rats. J Postgrad Med Edu Res 2016; 50 (1):18-21.

DOI: 10.5005/jp-journals-10028-1185

Published Online: 01-03-2016

Copyright Statement:  Copyright © 2016; The Author(s).


Abstract

Materials and methods

Forty rats of mean weight 247.7 gm were used in the study. Amylase levels were measured at 60 minutes (groups A and C) and at 120 minutes (groups B and D) of reperfusion. Erythropoietin was administered only in groups C and D.

Results

Erythropoietin administration kept non-significantly increased the A levels by 5.04 ± 6.12% (p = 0.3831). Reperfusion time kept non-significantly increased the A levels by 10.08 ± 5.95% (p = 0.0615). However, EPO administration and reperfusion time together produced a non-significant combined effect in keeping increased the A levels by 4.36 ± 3.65% (p = 0.2258)

Conclusion

Erythropoietin administration, reperfusion time and their interaction kept non-significantly short-term increased the amylase levels. The restorating effect of Epo is satisfactory, since it reduced the discrepancy from baseline values at non-significant level.

How to cite this article

Tsompos C, Panoulis C, Toutouzas K, Zografos G, Papalois A. The Effect of Erythropoietin on Amylase Levels during Ischemia-Reperfusion Injury in Rats. J Postgrad Med Edu Res 2016;50(1):18-21.


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