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VOLUME 53 , ISSUE 4 ( October-December, 2019 ) > List of Articles


Impact on Fertility in Patients with Hematological Malignancies and Bone Marrow Transplant

Gaurav Prakash, Chandan K Das

Keywords : Bone marrow transplant, Cancer, Chemotherapy, Fertility, Hematology, Preservation

Citation Information : Prakash G, Das CK. Impact on Fertility in Patients with Hematological Malignancies and Bone Marrow Transplant. J Postgrad Med Edu Res 2019; 53 (4):173-175.

DOI: 10.5005/jp-journals-10028-1337

License: CC BY-NC 4.0

Published Online: 01-06-2018

Copyright Statement:  Copyright © 2019; The Author(s).


With the rapidly improving outcome of patients suffering from hematologic disorders and cancers, there exists a rapidly widening gap of unmet need regarding fertility preservation in this group. Hematologic cancers make for a large proportion of all cancers in young patients and there are issues peculiar to hematologic neoplasms which are not observed by the patients suffering from solid tumors. The biggest challenge is seen with the patients undergoing hematologic stem cell transplants because it involves use of high doses of cytotoxic chemotherapy with or without radiation. In majority of these cases, the damage to gonadal function is irreversible. Each hematologic disorder in young patients poses a unique challenge regarding fertility preservation. In this review, we address some important aspects related to fertility in patients suffering from a few selected hematologic disorders.

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