Background: The existing literature on the mental health outcomes of frontline healthcare workers (HCWs) is silent over the psychosocial issues being faced by the housekeeping/hospital attendants (HAs) and sanitary attendants (SAs) who are also actively involved in coronavirus disease-2019 (COVID-19) patient care and in biomedical waste management. This group of HCWs can be considered as the “faceless corona warriors,” and their psychosocial issues needs to be focused upon too. Aim and objective: To evaluate the psychosocial issues and problems related to issues specific to carrying out duties in COVID-19 wards among the HAs and SAs. Materials and methods: An interview-based approach (cross-sectional assessment) conducted by healthcare professionals in the local languages of the HAs and SAs was followed. Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) were used to assess depression and anxiety, respectively. Along with it, a self-designed questionnaire was added to evaluate the different emotional states and problems faced by the HAs and SAs during their COVID-19 duty. Results: A total of 100 participants (62 HAs and 38 SAs) were enrolled for this study. Overall, 11% reported mild anxiety and 21% reported mild depressive symptoms (as per the GAD-7 and PHQ-9 grading) with an overall psychological morbidity of 25%. A significant proportion (one-third to one-fourth) of the participants reported negative emotional experiences, such as that of sadness, scared, anxious, loneliness, socially disconnectedness, being used, and feeling stigmatized for working in COVID areas. Overall, 40% of the participants were ‘very scared’ of infecting their family members and two-fifths (39%) reported that their family members were worried for “most of the time” about them getting ill. Further, about one-fifth (19%) of the participants had difficulty in learning the steps of donning and doffing of personal protective equipments (PPEs), and one-fourth (25%) reported forgetting the steps of donning and doffing process. More than half of the participants reported of work overload and hectic duty shifts, and majority of the participants reported feeling uncomfortable and “dizzy,” having headache, and feeling thirsty during duty hours while on PPEs. Conclusion: Our findings suggest that a substantial proportion of HAs and SAs have mild anxiety, depression, and several significant negative emotional states as well as family-related concerns during COVID-19 duty period and while under quarantine. They also reported significant and genuine problems related to PPEs usage and infection control measures. Timely steps in the form of appropriate mental health support as well as adequate counseling and reassurance during training can prove beneficial in allying the concerns of this group of HCWs engaged on COVID-19 duties. Key learning points: What is already known about this subject: • The existing literature on the mental health outcomes of healthcare workers on COVID-19 duties have mainly focused on the psychological morbidity among the doctors/physicians and nurses. • No data are currently available on the psychosocial issues and problems faced by the housekeeping/hospital attendants (HAs) and sanitary attendants (SAs) who are actively involved in patient welfare and in biomedical waste management of COVID-19 patients. What this study adds: • Our findings highlight the presence of anxiety and depressive symptoms (mild in intensity), and negative emotional states in a significant proportion of HAs and SAs on COVID-19 duties. • We also found significant evidence related to the family concerns and problems being faced by this group of healthcare workers (HCWs) related to infection control measures and personal protective equipment's usage/training. What impact this may have on practice or policy: • Our findings highlight the importance of mental health support, proactive reassurance, and counseling which are essential to allay the concerns and anxiety of this group of HCWs. • The mental health issues of this group of HCWs needs to be addressed as for other front line HCWs (doctors and nurses).