Peripheral limb gangrene in neonates presenting soon after birth is rare and exact etiology could not be ascertained in majority. In order to make an important contribution to the limited literature on this topic, we report rare and unique presentation of peripheral limb gangrene in two neonates soon after birth (on day 1 of life) involving lower limbs. The etiology could not be ascertained, despite extensive workup. Both cases were managed with supportive care and low-molecular-weight heparin and developed auto-amputation of toes.
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