Lemierre\'s syndrome is a rare condition, sharing a symptom spectrum with some other viral diseases which can sometimes mask the diagnosis of the syndrome. It is important to keep a low threshold of the possibility of the syndrome, especially in someone who develops features of systemic upset after a sore throat. If undiagnosed and left untreated the syndrome can be fatal and can have severe multiorgan complications requiring various forms of medical and surgical interventions. We present the case of Lemierre\'s syndrome in a 32-year-old man who was successfully treated during an inpatient stay involving intensive care unit, followed by a community-based course of antimicrobial therapy for several weeks.
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