Journal of Postgraduate Medicine, Education and Research

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VOLUME 57 , ISSUE 3 ( July-September, 2023 ) > List of Articles


Superiority Trial: Sample Size Calculation and its Interpretation in Health Research

Ashok Kumar, Rimesh Pal, Manisha Nagi, Maninderdeep Kaur, Sukhpal Kaur

Keywords : Health research, Randomized clinical trial, Sample size calculation, Superiority trial

Citation Information : Kumar A, Pal R, Nagi M, Kaur M, Kaur S. Superiority Trial: Sample Size Calculation and its Interpretation in Health Research. J Postgrad Med Edu Res 2023; 57 (3):131-136.

DOI: 10.5005/jp-journals-10028-1623

License: CC BY-NC 4.0

Published Online: 26-07-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Sample size calculation in any randomized clinical trial is an essential step to avoid over- and underestimation of the outcomes. Health researchers should prior estimate the sample size which helps in the validity and reliability of the superiority trial. This paper highlights the step-by-step calculation of sample size in a superiority trial using appropriate and simple formulas and its interpretation with suitable examples in different conditions so that health researchers can better understand this important part of a clinical trial.

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