Fertility in Women with BRCA1 and 2 Mutations - Do We Need to be Concerned?

Dr Divyesh Kumar; Dr Bhavana Rai

doi:10.5005/jpmer-53-4-iii

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Fertility in Women with BRCA1 and 2 Mutations - Do We Need to be Concerned?

Dr Divyesh Kumar, Dr Bhavana Rai

Citation Information : Kumar DD, Rai DB. Fertility in Women with BRCA1 and 2 Mutations - Do We Need to be Concerned?. J Postgrad Med Edu Res 2019; 53 (4).

DOI: 10.5005/jpmer-53-4-iii

License: CC BY-NC 4.0

Published Online: 01-06-2018

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Grynberg M, Raad J, Comtet M, et al. Future Oncol. 2018;14(5):483-490.
Antoniou A, Pharoah PD, Narod S, et al. Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies. Am J Hum Genet. 2003;72:1117-1130.
Rzepka-Gorska I, Tarnowski B, Chudecka-Głaz A, et al. Premature menopause in patients with BRCA1 gene mutation. Breast Cancer Res Treat. 2006;100:59-63.
Johnson L, Sammel MD, Domchek S, et al. Anti-Mullerian hormone levels are lower in BRCA2 mutation carriers. Fertil. Steril. 107(5):1256-1265.
Wang ET, Pisarska MD, Bresee C, et al. BRCA1 germline mutations may be associated with reduced ovarian reserve. Fertil Steril. 2014;102(6):1723-1728.
Shenfield F, Pennings G, Devroey P, et al. ESHRE ethics task force. Taskforce 5: preimplantation genetic diagnosis. Hum Reprod. 2003;18:649-651.

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