Journal of Postgraduate Medicine, Education and Research

Register      Login

VOLUME 58 , ISSUE 2 ( April-June, 2024 ) > List of Articles

CASE REPORT

A Case of Massive Envenomation with Bee Sting: A Case Report

Shreedhara Nagol Shekharappa, Srivatsan Ranga Chari

Keywords : Anaphylaxis, Bee sting, Case report, Envenomation, Rhabdomyolysis, Urine alkalinization

Citation Information : Shekharappa SN, Chari SR. A Case of Massive Envenomation with Bee Sting: A Case Report. J Postgrad Med Edu Res 2024; 58 (2):80-82.

DOI: 10.5005/jp-journals-10028-1654

License: CC BY-NC 4.0

Published Online: 05-07-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Envenomation from Hymenoptera stings, including honeybees, wasps, and hornets, usually results in local erythema and edema. Envenomation with bee stings can have varied presentations, from local erythema and systemic reactions (intravascular hemolysis, rhabdomyolysis, acute kidney injury, and liver dysfunction) to anaphylaxis, depending on the number of stings, comorbidities of the patient, and prior sensitization to bee stings. We report a case of massive bee sting envenomation with over 200 bee stings on a patient who presented to our hospital and developed rhabdomyolysis, liver dysfunction, and an elevated troponin I. Early interventions with adequate fluid resuscitation, urine alkalinization, and hepatoprotective measures resulted in a favorable outcome.


HTML PDF Share
  1. Casale TB, Burks AW. Clinical practice. Hymenoptera-sting hypersensitivity. N Engl J Med 2014;370(15):1432–1439. DOI: 10.1056/NEJMcp1302681
  2. Silva GBD Junior, Vasconcelos AG Junior, Rocha AMT, et al. Acute kidney injury complicating bee stings - a review. Rev Inst Med Trop Sao Paulo 2017;59:e25. DOI: 10.1590/S1678-9946201759025
  3. Mingomataj EÇ, Bakiri AH, Ibranji A, et al. Unusual reactions to hymenoptera stings: what should we keep in mind? Clin Rev Allergy Immunol 2014;47(1):91–99. DOI: 10.1007/s12016-014-8434-y
  4. Temizoz O, Celik Y, Asil T, et al. Stroke due to bee sting. Neurologist 2009;15(1):42–43. DOI: 10.1097/NRL.0b013e31818c7251
  5. Pucca MB, Cerni FA, Oliveira IS, et al. Bee updated: current knowledge on bee venom and bee envenoming therapy. Front Immunol 2019;10:2090. DOI: 10.3389/fimmu.2019.02090
  6. Wehbe R, Frangieh J, Rima M, et al. Bee venom: overview of main compounds and bioactivities for therapeutic interests. Molecules 2019;24(16): DOI: 10.3390/molecules24162997
  7. Chen J, Guan SM, Sun W, et al. Melittin, the major pain-producing substance of bee venom. Neurosci Bull 2016;32(3):265–272. DOI: 10.1007/s12264-016-0024-y
  8. Raghuraman H, Chattopadhyay A. Melittin: a membrane-active peptide with diverse functions. Biosci Rep 2007;27(4-5):189–223. DOI: 10.1007/s10540-006-9030-z
  9. Mingarro I, Pérez-Payá E, Pinilla C, et al. Activation of bee venom phospholipase A2 through a peptide-enzyme complex. FEBS Lett 1995;372(1):131–134. DOI: 10.1016/0014-5793(95)00964-b
  10. Toledo LFM, Moore DCBC, Caixeta DMDL, et al. Multiple bee stings, multiple organs involved: a case report. Rev Soc Bras Med Trop 2018;51(4):560–562. DOI: 10.1590/0037-8682-0341-2017
  11. Almeida RA, Olivo TE, Mendes RP, et al. Africanized honeybee stings: how to treat them. Rev Soc Bras Med Trop 2011;44(6):755–761. DOI: 10.1590/s0037-86822011000600020
  12. Fitzgerald KT, Flood AA. Hymenoptera stings. Clin Tech Small Anim Pract 2006;21(4):194–204. DOI: 10.1053/j.ctsap.2006.10.002
  13. Dart RC. Medical Toxicology. Philadelphia, Pennsylvania: Lippincott Williams and Wilkins; 2004.
  14. Nisahan B, Selvaratnam G, Kumanan T. Myocardial injury following multiple bee stings. Trop Doct 2014;44(4):233–234. DOI: 10.1177/0049475514525606
  15. Hughes RL. A fatal case of acute renal failure from envenoming syndrome after massive bee attack: a case report and literature review. Am J Forensic Med Pathol 2019;40(1):52–57. DOI: 10.1097/PAF.0000000000000451
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.