VOLUME 58 , ISSUE 3 ( July-September, 2024 ) > List of Articles
Venkat S Chittapragada, Nandita B Kakkar, Payal Charaya, Arkit D Singh, Navneet Sharma, Saurabh C Sharda
Keywords : Case report, Chikungunya, Hemorrhages, Myocarditis, Klebsiella pneumonia, Pulmonary edema, Thrombotic microangiopathy
Citation Information : Chittapragada VS, Kakkar NB, Charaya P, Singh AD, Sharma N, Sharda SC. Catastrophic Presentation of Chikungunya—Autopsy Findings: A Case Report. J Postgrad Med Edu Res 2024; 58 (3):125-127.
DOI: 10.5005/jp-journals-10028-1672
License: CC BY-NC 4.0
Published Online: 05-11-2024
Copyright Statement: Copyright © 2024; The Author(s).
A 36-year-old male truck driver presented to the emergency department with fever of 5 days’ duration, shortness of breath, and an episode of seizure 1 day ago. The fever was not associated with chills, rigor, or rash and was relieved with medication. One day prior to admission, the patient started experiencing shortness of breath, which was acute in onset and rapidly progressed to modified Medical Research Council (mMRC) grade IV. It was associated with cough and expectoration but not with chest pain or palpitations. He was admitted to an outside facility, where he was managed with antibiotics and fluids. Due to worsening symptoms, he was referred to our center, where he had a brief hospital stay of about 3 hours. Renal/liver function tests, coagulogram, and electrolytes were deranged. Thrombocytopenia was present. Blood cultures grew multidrug-resistant (MDR) Klebsiella pneumoniae. Soon after, he suffered a cardiac arrest and succumbed to his illness. A partial autopsy was performed, which revealed florid myocarditis and hemorrhages in the heart, thrombotic microangiopathy (TMA) in the kidneys and liver, pulmonary artery thrombi, pulmonary edema, hemorrhage, and congestion in all organs. Viral polymerase chain reaction (PCR) was positive for chikungunya (CHIKV) virus.
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